Current Protocols Editorial Board: Protein Science
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John E. Coligan Dr. Coligan received his Ph.D. from Indiana University and did postdoctoral research at the City of Hope Research Institute. After 2 years as an assistant professor at Rockefeller University, he became a founding member of the Laboratory of Immunogenetics, NIAID, NIH. He has served as head of the Biological Resources Branch and Laboratory of Molecular Structure. In 1998, he joined the Laboratory of Allergic Diseases and became chief of the Receptor Cell Biology Section. In 2007, this section moved to the Laboratory of Immunogenetics. The primary focus of Dr. Coligan's research is the receptors that dictate natural killer (NK) cell function. NK cells are an integral component of the innate immune response against infectious diseases and malignant transformation. In addition to their ability to lyse infected and transformed cells, they serve as a potent source of cytokines for potentiating both the innate and adaptive immune responses. His interests encompass all facets of factors that regulate NK-cell receptor expression, ligand recognition, signal transduction, and intracellular trafficking, with particular emphasis on the NKG2 family of receptors. |
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Ben M. Dunn Ben Dunn was born in New Jersey in 1945. After his B.S. in Chemistry from the University of Delaware, he earned the Ph.D. in Bioorganic Chemistry in 1971 from the University of California at Santa Barbara, where he worked under Professor Tom Bruice. He did his post-doctoral work in the laboratory of Christian Anfinsen from 1971-1973 and was a staff fellow from 1973-1974, when he joined the Department of Biochemistry at the University of Florida as Assistant Professor. He rose through the ranks there and is now Distinguished Professor of Biochemistry and Molecular Biology. He is supported by NIH for studies of HIV-1 Protease and has contributed to studies on other proteolytic enzymes, including the malarial plasmepsins. His research interests are in protein structure and function as well as in drug design/discovery for therapy of infectious diseases. |
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David W. Speicher Dr. Speicher received his Ph.D. training in Biochemistry at the Pennsylvania State University, followed by postdoctoral training in the Pathology Department of the Yale Medical School. He is currently Professor and Director of the Systems and Computational Biology Center at the Wistar Institute, a private non-profit research institute located on the University of Pennsylvania campus in west Philadelphia. One major focus of his research program is development of novel multi-dimensional proteome profiling methods and application of these methods to identify novel serological diagnostic markers of cancer and other human diseases. His laboratory was an active participant in the Human Proteome Organization's Plasma Proteome Pilot Project and a multi-institutional EDRN-WHI pilot project to discovery plasma biomarkers of colon cancer. In addition, his research group uses protein biochemical and biophysical techniques to study protein structure-function relationships of membrane-associated proteins. He serves on a number of scientific advisory boards and NIH study sections, and has presented more than 80 invited lectures and seminars around the world. He has published more than 125 peer-reviewed research manuscripts and 45 book chapters or reviews. He edited a book entitled Proteome Research--Interpreting the Genome, serves on a number of editorial boards, including the journals Proteomics, Analytical Biochemistry, Biomarker Insights and PharmaGenomics, and is a senior editor for Cancer Research. |
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Paul T. Wingfield Dr. Wingfield, a native of Great Britain, has directed the Protein Expression Laboratory since its inception in 1989. In 1997, he received the NIH Director's Award for designing and establishing the Laboratory. Previously, Dr. Wingfield was department head of protein chemistry at Glaxo Institute for Molecular Biology (formerly Biogen SA) in Geneva, Switzerland, where he spent nine years perfecting and using techniques for the production of recombinant protein and their structural characterization. Earlier, he was a staff scientist in the biological structures division of the European Molecular Biology Laboratory, Heidelberg, Germany. Dr. Wingfield received his doctorate from Dundee University in Scotland and was a postdoctoral scholar in biological chemistry at the University of California, Los Angeles. Dr. Wingfield has published about 170 articles in national and international scientific journals. |
