Current Protocols in Pharmacology

Editors & Contributors

Editors & Contributors

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EDITORIAL BOARD

S.J. Enna (Editor-in-Chief)
University of Kansas Medical Center
Kansas City, Kansas

Michael Williams (Editor-in-Chief)
Lake Forest, Illinois

Roger Frechette
MaxThera
Beverly, MA

Terry Kenakin
GlaxoSmithKline
Research Triangle Park, North Carolina

Paul McGonigle
PsychoGenics
Tarrytown, New York

Bruce Ruggeri
Cephalon
West Chester, Pennsylvania

GUEST EDITOR

Brendan J. Canning
Johns Hopkins Asthma and Allergy Center
Baltimore, Maryland

PAST EDITORS

John F. Barrett
Merck Research Laboratories
Rahway, New Jersey

James Ellis
Sirtris
Cambridge, MA

John W. Ferkany
Surface Logix
Brighton, MA

Paul Moser
Porsolt and Partners Pharmacology
Boulogne Billancourt, France

Roger D. Porsolt
Porsolt and Partners Pharmacology
Boulogne Billancourt, France

James P. Sullivan
Abbott Laboratories
Abbott Park, Illinois

CONTRIBUTORS

Cory Abate-Shen
Columbia University Medical Center
Herbert Irving Comprehensive Cancer Center
New York, New York

Worku Abebe
Medical College of Georgia
School of Dentistry
Augusta, Georgia

Najah Abi-Gerges
Safety Assessment UK
AstraZeneca R&D
Cheshire, United Kingdom

Susan M. Abmayr
The Stowers Institute for Medical Research
Kansas City, Missouri

Prasad S. Adusumilli
Memorial Sloan-Kettering Cancer Center
New York, New York

Lisa D. Aimone
Cephalon
West Chester, Pennsylvania

Daniel H. Albert
Abbott Laboratories
Abbott Park, Illinois

Pēteris Alberts
Biovitrum
Stockholm, Sweden

Stephen P.H. Alexander
University of Nottingham Medical School
Nottingham, United Kingdom

Richard H. Alper
University of Kansas School of Medicine
Kansas City, Kansas

Charles Anderson
Discovery Biology
Pfizer Central Research
Sandwich, United Kingdom

David J. Anderson
Abbott Laboratories
Abbott Park, Illinois

Karl-Erik Andersson
Lund University Hospital
Lund, Sweden

Emile Andriambeloson
Neurofit SAS
Illkirch, France

Habib R. Ansari
West Virginia University
Morgantown, West Virginia

Paul Aravich
Eastern Virginia Medical School and Veterans Affairs Medical Center
Norfolk and Hampton, Virginia

Scott Armstrong
Theravance
South San Francisco, California

Hitoshi Ashida
Graduate School of Agricultural Science
Kobe University
Kobe, Japan

Mark A. Ator
Cephalon
West Chester, Pennsylvania

Kenneth L. Audus
University of Kansas
Lawrence, Kansas

Daniel Auld
Douglas Hospital Research Center and McGill University
Montreal, Canada

Anthony W. Bannon
Amgen
Thousand Oaks, California

John F. Barrett
Merck Research Laboratories
Rahway, New Jersey

Daniel E. Bassi
Fox Chase Cancer Center
Philadelphia, Pennsylvania

Arnab Basu
Microbiotix
Worcester, Massachusetts

Simon T. Bate
GlaxoSmithKline
Harlow, Essex, United Kingdom

Melissa S. Beck-Westermeyer
University of Kansas
Lawrence, Kansas

Bernard Beer
DOV Pharmaceutical
Hackensack, New Jersey

Marie K. Hoeger Bement
University of Iowa
Iowa City, Iowa

Dietmar Benke
University of Zurich
Zurich, Switzerland

Gary J. Bennett
McGill University
Montreal, Canada

James R. Berenson
Institute for Myeloma and Bone Cancer Research
West Hollywood, California

Kelly A. Berg
University of Texas Health Science Center
San Antonio, Texas

Daniel Bertrand
Centre Médical Universitaire
Geneva, Switzerland

Sonia Bertrand
Centre Médical Universitaire
Geneva, Switzerland

Ilona Berzetei-Gurske
SRI International
Menlo Park, California

Anne-Marie Bétat
Centre International de Toxicologie (CIT)
Evreux, France

John A. Beutler
National Cancer Institute
Frederick, Maryland

Elisabeth Y. Bijlsma
Utrecht Institute for Pharmaceutical Sciences and
Rudolf Magnus Institute for Neuroscience
Utrecht University
Utrecht, The Netherlands

Julien Bindler
Neurofit SAS
Illkirch, France

W. Robert Bishop
Schering-Plough Research Institute
Kenilworth, New Jersey

Frank E. Blaney
GlaxoSmithKline
Harlow, Essex, United Kingdom

Kathleen M.K. Boje
University of Buffalo, School of Pharmacology
Buffalo, New York

Ronald T. Borchardt
University of Kansas
Lawrence, Kansas

Aurélie Boucard
Centre International de Toxicologie (CIT)
Evreux, France

Terry L. Bowlin
Microbiotix
Worcester, Massachusetts

H. Neal Bramson
GlaxoSmithKline
Research Triangle Park, North Carolina

Allan R. Brasier
University of Texas
Galveston, Texas

Timothy J. Brennan
University of Iowa College of Medicine
Iowa City, Iowa

Nathalie Breysse
Wyeth Research
Discovery Neuroscience
Princeton, New Jersey

Denis Bricout
Development Center
Cephalon France
Maisons Alfort, France

Geneviève Brossard
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Jonathan M. Brotchie
Toronto Western Research Institute and Atuka Ltd.
Toronto, Ontario, Canada

Emmanuel Brousseau
Development Center
Cephalon France
Maisons Alfort, France

David R. Brown
Departments of Veterinary and Biomedical Sciences (DRB) and Animal Science (SMO)
University of Minnesota
St. Paul, Minnesota

William A. Brown
Amgen
Seattle, Washington

Neil Brunton
Discovery Biology
Pfizer Central Research
Sandwich, United Kingdom

Lorrene A. Buckley
Lilly Research Laboratories
Greenfield, Indiana

Stephen Buratowski
Harvard Medical School
Boston, Massachusetts

Randy Burd
University of Arizona
Tucson, Arizona

David J. Burns
Abbott Laboratories
Abbott Park, Illinois

Mark Bushfield
Cambridge Drug Discovery
Cambridge, United Kingdom

David B. Bylund
University of Nebraska Medical Center
Omaha, Nebraska

Fergus R. Byrne
Amgen
Thousand Oaks, California

Richard A. Campbell
Institute for Myeloma and Bone Cancer Research
West Hollywood, California

Brendan J. Canning
The Johns Hopkins Medical Institutions
Baltimore, Maryland

Galen Carey
Schering-Plough Research Institute
Kenilworth, New Jersey

Brett L. Carlson
Mayo Clinic
Rochester, Minnesota

Andrés E. Carrasceo
Buenos Aires Medical School
Buenos Aires, Argentina

Kevin M. Carrick
GlaxoSmithKline
Research Triangle Park, North Carolina

Michael J. Carrozza
Pennsylvania State University
University Park, Pennsylvania

Anthony Carter
Discovery Biology
Pfizer Central Research
Sandwich, United Kingdom

Joel A. Cassel
Adolor Corporation
Exton, Pennsylvania

James V. Cassella
Neurogen
Branford, Connecticut

Vincent Castagné
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Neil A. Castle
Icagen
Durham, North Carolina

Icilio Cavero
Bonneuil sur Marne, France

Jean-Guy Chabot
Douglas Hospital Research Center and McGill University
Montreal, Canada

Leslie J. Charles
3M Pharmaceuticals
St. Paul, Minnesota

Steven J. Charlton
Novartis Institutes for Biomedical Research
Horsham, West Sussex, United Kingdom

Prasoon Chaturvedi
Surface Logix
Brighton, Massachusetts

Naz Chaudary
Ontario Cancer Institute/Princess Margaret Hospital
and University of Toronto
Toronto, Ontario, Canada

June Chen
Allergan
Irvine, California

Lewis A. Chodosh
University of Pennsylvania
Philadelphia, Pennsylvania

Agnes Choppin
Theravance
South San Francisco, California

Arthur Christopoulos
Monash University
Victoria, Australia

Jin Mo Chung
Marine Biomedical Institute
Galveston, Texas

Dennis J. Church
Serono Pharmaceutical Research Institute
Plan-les-Ouates, Switzerland

Jill Clampit
Abbott Laboratories
Abbott Park, Illinois

William P. Clarke
University of Texas Health Science Center
San Antonio, Texas

Martine Clozel
Actelion Pharmaceuticals
Allschwil, Switzerland

Donald M. Coen
Harvard Medical School
Boston, Massachusetts

Robert A. Coleman
Pharmagene Laboratories
Royston, United Kingdom

Christos Colovos
Memorial Sloan-Kettering Cancer Center
New York, New York

J. Patrick Condreay
GlaxoSmithKline Molecular Discovery Research
Research Triangle Park, North Carolina

Peter Condron
Agency for Science, Technology, and Research (A*STAR)
Singapore

Alex C. Conner
Aston University
Aston Triangle, United Kingdom

Denise C. Connolly
Fox Chase Cancer Center
Philadelphia, Pennsylvania

Carlos Cordon-Cardo
Columbia University Medical Center
Herbert Irving Comprehensive Cancer Center
New York, New York

Mauro Corsi
Glaxo Wellcome
Verona, Italy

Bryan F. Cox
Abbott Laboratories
Abbott Park, Illinois

Richard F. Cox
GlaxoSmithKline
Research Triangle Park, North Carolina

Mark Crawford
CEREP
Rueil-Malmaison, France

Stephen L. Crooks
3M Pharmaceuticals
St. Paul, Minnesota

William J. Crumb
Zenas Technologies
New Orleans, Louisiana

Brian S. Cummings
Medical University of South Carolina
Charleston, South Carolina

Stacie A. Dalrymple
Roche Bioscience
Palo Alto, California

Alex Daniels
Glaxo Wellcome Research and Development
Research Triangle Park, North Carolina

Gavin Davey
Trinity College
Dublin, Ireland

Steven K. Davidsen
Abbott Laboratories
Abbott Park, Illinois

Michael W. Decker
Abbott Laboratories
Abbott Park, Illinois

Robert N. DeHaven
Adolor
Exton, Pennsylvania

Diane L. DeHaven-Hudkins
Adolor
Exton, Pennsylvania

William E. Delaney, IV
Gilead Sciences
Foster City, California

Enock Delaporte
Merck Research Laboratories
West Point, Pennsylvania

Chengjun Deng
Memory Pharmaceuticals
Montvale, New Jersey

Errol B. De Souza
Neurocrine Biosciences
San Diego, California

Michael De Vivo
Memory Pharmaceuticals
Montvale, New Jersey

Vijay Dhawan
NitroMed
Lexington, Massachusetts

Amy DiCamillo
Cephalon
West Chester, Pennsylvania

Xiao-Wei Dong
Schering-Plough Research Institute
Kenilworth, New Jersey

Michael A. Dorato
Lilly Research Laboratories
Greenfield, Indiana

Sylvain Doré
Douglas Hospital Research Center and McGill University
Montreal, Canada

Karen Dorso
Merck
Rahway, New Jersey

Natasha Dow
Covance Laboratories
Madison, Wisconsin

Paul Dow
Covance Laboratories
Madison, Wisconsin

Dennis Dowhan
Baylor College of Medicine
Houston, Texas

Mark R. Dowling
Novartis Institutes for Biomedical Research
Horsham, West Sussex, United Kingdom

Gregory P. Dubé
Biopure Corporation
Cambridge, Massachusetts

Joffrey Ducroq
Université de Caen
Boulogne-Billancourt, France

Nicola Duggan
Neurocrine Biosciences
San Diego, California

Ronald S. Duman
Yale University School of Medicine
Connecticut Mental Health Center
New Haven, Connecticut

Thomas V. Dunwiddie
Veterans Administration Medical Research Service
Denver, Colorado

Nicholas Dürmüller
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Emir Duzic
Cephalon
West Chester, Pennsylvania

Richard Eglen
Theravance
South San Francisco, California

James L. Ellis
Surface Logix
Brighton, Massachusetts

S.J. Enna
University of Kansas Medical Center
Kansas City, Kansas

Michael Entzeroth
Agency for Science, Technology, and Research (A*STAR)
Singapore

Timothy A. Esbenshade
Abbott Laboratories
Abbott Park, Illinois

Nicholas Evans
GlaxoSmithKline Research
Harlow, United Kingdom

Timothy M. Fan
University of Illinois at Urbana-Champaign
Urbana, Illinois

John W. Ferkany
Surface Logix
Brighton, Massachusetts

Jeffrey Fernandez
Johnson & Johnson Pharmaceutical Research and Development
Raritan, New Jersey

Katherine W. Figueroa
Johnson & Johnson Pharmaceutical
La Jolla, California

Sandra E. File
King's College London
London, United Kingdom

Horst Flotow
Agency for Science, Technology, and Research (A*STAR)
Singapore

Roy Forster
Centre International de Toxicologie (CIT)
Evreux, France

John J. Fortin
Tropix
Bedford, Massachusetts

Gerard B. Fox
Abbott Laboratories
Abbott Park, Illinois

Alan Frazer
The Audie L. Murphy Memorial Hospital Division
University of Texas Health Science Center
San Antonio, Texas

Christelle Froger
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Guillaume Froget
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Eric S. Furfine
Glaxo Wellcome Research and Development
Research Triangle Park, North Carolina

David J. Gallacher
Johnson & Johnson
Beerse, Belgium

Sean Gallagher
Motorola Phoenix Applied Research Center
Tempe, Arizona

Gary E. Gallick
The University of Texas M. D. Anderson Cancer Center
Houston, Texas

Jinnian Gao
University of Kansas
Lawrence, Kansas

Maciej Gasior
Cephalon
West Chester, Pennsylvania

L. Cristina Gavrilescu
Tufts Medical Center
Boston, Massachusetts

G. F. Gebhart
University of Iowa
Iowa City, Iowa

Robert Giacobbe
Merck
Rahway, New Jersey

William J. Giardina
Abbott Laboratories
Abbott Park, Illinois

Thierry Giboulot
Development Center
Cephalon France
Maisons Alfort, France

James K. Gierse
Searle Research and Development
Chesterfield, Missouri

Gary A. Gintant
Abbott Laboratories
Abbott Park, Illinois

Dennis Girard
Pfizer Global Research and Development
Groton, Connecticut

Michael Godes
Center for Cardiovascular Research
Institute of Pharmacology
Berlin, Germany

Aaron S. Goetz
GlaxoSmithKline
Research Triangle Park, North Carolina

Sonia Goineau
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Ronald L. Goldberg
Novartis Institute of Biomedical Research
Summit, New Jersey

Robert Goldstein
Tufts Medical Center
Boston, Massachusetts

Murali Gopalakrishnan
Abbott Laboratories
Abbott Park, Illinois

Georgianna Gould
University of Texas Health Science Center
San Antonio, Texas

Karen J. Gregory
Monash University
Victoria, Australia

Dimitri E. Grigoriadis
Neurocrine Biosciences
San Diego, California

Lucianne Groenink
Utrecht Institute for Pharmaceutical Sciences and
Rudolf Magnus Institute for Neuroscience
Utrecht University
Utrecht, The Netherlands

Stephanie J. Gros
University Medical Center Hamburg-Eppendorf
Hamburg, Germany

Garrett J. Gross
Medical College of Wisconsin
Milwaukee, Wisconsin

Philippe Guillaume
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Clarence Hale
Amgen
Thousand Oaks, California

Petro Halkowycz
Memory Pharmaceuticals
Montvale, New Jersey

Arthur A. Hancock
Abbott Laboratories
Abbott Park, Illinois

Anna G. Haramis
EMBL
Heidelberg, Germany

Wallace Harrington
Glaxo Wellcome Research and Development
Research Triangle Park, North Carolina

David A. Hartman
Ricerca
Concord, Ohio

S.F. Hastings
Scottish Biomedical
Glasgow, Scotland, United Kingdom

Carine Hautbois
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Brian E. Hawes
Schering-Plough Research Institute
Kenilworth, New Jersey

Anne-Marie Hay
Porsolt & Partners Pharmacology
Le Kremlin-Bicêtre, France

Debbie L. Hay
Aston University
Aston Triangle, United Kingdom

Douglas W. P. Hay
SmithKline Beecham Pharmaceuticals
King of Prussia, Pennsylvania

David W. Hedley
Ontario Cancer Institute/Princess Margaret Hospital
and University of Toronto
Toronto, Ontario, Canada

Petter Hedlund
Lund University Hospital
Lund, Sweden

Sharath S. Hegde
Theravance
South San Francisco, California

Harvey H. Hensley
Fox Chase Cancer Center
Philadelphia, Pennsylvania

Stéphane Hervé
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Patrick Hess
Actelion Pharmaceuticals
Allschwil, Switzerland

Hiroshi Hiasa
University of Minnesota Medical School-Twin Cities
Minneapolis, Minnesota

Guy A. Higgins
BioQuest Innovations
Toronto, Ontario, Canada

Bridget T. Hill
Centre de Recherche Pierre Fabre
Castres, Cedex, France

Jeanette R. Hill
Ricerca Biosciences
Concord, Ohio

Richard P. Hill
Ontario Cancer Institute/Princess Margaret Hospital
and University of Toronto
Toronto, Ontario, Canada

Diane C. Hoffman
Neurogen
Branford, Connecticut

Melinda Hollingshead
National Cancer Institute
Frederick, Maryland

Paul Honegger
Universite de Lausanne
Lausanne, Switzerland

Marie Honore
Abbott Laborotories
Abbott Park, Illinois

Peter J. Houghton
St. Jude Children's Research Hospital
Memphis, Tennessee

Youming Huan
Mount Sinai School of Medicine
New York, New York

Mingjun Huang
Achillion Pharmaceuticals
New Haven, Connecticut

Isabelle Hubert
Porsolt & Partners Pharmacology
Le Kremlin-Bicêtre, France

Erin D. Hugger
University of Kansas
Lawrence, Kansas

Magdeleine Hung
Gilead Sciences
Foster City, California

Leyla Hussein
Safety Assessment UK
AstraZeneca R&D
Cheshire, United Kingdom

Diane M. Ignar
GlaxoSmithKline
Research Triangle Park, North Carolina

David Janero
NitroMed
Lexington, Massachusetts

Michael F. Jarvis
Abbott Laboratories
Abbott Park, Illinois

Channa Jayawickreme
GlaxoSmithKline
Research Triangle Park, North Carolina

Michael R. Jirousek
Abbott Laboratories
Abbott Park, Illinois

Bo G. Johansson
Somedic
Hörby, Sweden

Daniel M. Johnson
Cardiovascular Research Institute Maastricht
Maastricht University Medical Centre
Maastricht, The Netherlands

Declan N.C. Jones
GlaxoSmithKline
Harlow, Essex, United Kingdom

R. Carter W. Jones, III
University of Iowa
Iowa City, Iowa

Robert L. Jones
The Chinese University of Hong Kong
Shatin, Hong Kong

Susan Jones-Bolin
Cephalon
West Chester, Pennsylvania

Stefan S. Kachala
Memorial Sloan-Kettering Cancer Center
New York, New York

Jason A. Kahana
Dana-Farber Cancer Institute
Boston, Massachusetts

Mikhail Kalinichev
GlaxoSmithKline
Harlow, Essex, United Kingdom

R.H. Kant
AccuScan/Omnitech Instruments
Columbus, Ohio

Satyabrata Kar
Douglas Hospital Research Center and McGill University
Montreal, Canada

William Karbon
Amgen
Thousand Oaks, California

Vladimir V. Karpitskiy
Washington University School of Medicine
St. Louis, Missouri

D. Nedra Karunaratne
University of Kansas
Lawrence, Kansas

David A. Katz
Abbott Laboratories
Abbott Park, Illinois

Kyuichi Kawabata
Graduate School of Agricultural Science
Kobe University
Kobe, Japan
and Fukui Prefectural University
Fukui, Japan

Kengo Kawasaki
Food Science Research Center
House Wellness Foods Corporation
Hyogo, Japan

Zehra Kaymakcalan
Abbott Bioresearch Center
Worcester, Massachusetts

Lois J. Kehl
University of Minnesota
Minneapolis, Minnesota

John H. Kehne
Neurogen
Branford, Connecticut

John J. Kelly
University of South Alabama College of Medicine
Mobile, Alabama

Terry Kenakin
GlaxoSmithKline Research Institute
Research Triangle Park, North Carolina

David Kendall
University of Nottingham Medical School
Nottingham, United Kingdom

Barry Kenny
Cambridge Drug Discovery
Cambridge, United Kingdom

Eugene S. Kim
Baylor College of Medicine
Texas Children's Hospital
Houston, Texas

Sun Jin Kim
The University of Texas M. D. Anderson Cancer Center
Houston, Texas

Robert E. Kingston
Massachusetts General Hospital and Harvard Medical School
Boston, Massachusetts

Patrick Kitabgi
Hopital St-Antoine
Paris, France

Steven R. Kleeberger
Laboratory of Respiratory Biology
National Institute of Environmental Health Sciences
National Institutes of Health
Research Triangle Park, North Carolina

A.J.P. Klein-Szanto
Fox Chase Cancer Center
Philadelphia, Pennsylvania

Carol M. Koboldt
Searle Research and Development
Chesterfield, Missouri

Karla K. Kopec
Cephalon
West Chester, Pennsylvania

Martha F. Kramer
Harvard Medical School
Boston, Massachusetts

Anna Kruczynski
Centre de Recherche Pierre Fabre
Castres, Cedex, France

Michael J. Kuhar
Yerkes Regional Primate Research Center
Atlanta, Georgia

Steven M. Kwasny
Microbiotix
Worcester, Massachusetts

Pierre Lacroix
Porsolt & Partners Pharmacology
Boulogne Billancourt, France

Nathaniel R. Landau
The Salk Institute for Biological Studies
La Jolla, California

Katie Leach
Monash University
Parkville, Victoria, Australia

Kathleen M. Lee
Scios
Sunnyvale, California

Pamela Legrand
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Kristin M. Lehet
Roswell Park Cancer Institute
Buffalo, New York

Martine Lemaire
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

James M. Lenhard
GlaxoSmithKline
Research Triangle Park, North Carolina

Beth Levant
University of Kansas Medical Center
Kansas City, Kansas

Liza Leventhal
EnVivo Pharmaceuticals
Watertown, Massachusetts

Jeffrey Liebman
Novartis Institute of Biomedical Research
Summit, New Jersey

Arnold S. Lippa
DOV Pharmaceutical
Hackensack, New Jersey

Morgan T. Lippa
DOV Pharmaceutical
Hackensack, New Jersey

Yong Liu
Pfizer Global Research & Development
Ann Arbor, Michigan

Xiaohong Liu
Gilead Sciences
Foster City, California

Richard B. Lock
Children's Cancer Institute Australia for Medical Research
Randwick, New South Wales, Australia

John P. Long
University of Iowa
Iowa City, Iowa

Marge T. Lorang
Neurocrine Biosciences
San Diego, California

Rex Lovrien
University of Minnesota
St. Paul, Minnesota

Lily D. Lu
Cephalon
West Chester, Pennsylvania

Thomas Lubben
Abbott Laboratories
Abbott Park, Illinois

Mark A. Luttmann
SmithKline Beecham Pharmaceuticals
King of Prussia, Pennsylvania

Simon J. Lydford
Molecular Devices
Winnersh, United Kingdom

Matthias Mack
Ludwig-Maximilians-University of Munich
Munich, Germany

S.J. MacKenzie
Scottish Biomedical
Glasgow, Scotland, United Kingdom

Carlo Alberto Maggi
Menarini Ricerche
Florence, Italy

Jeanne Magram
Boehringer Ingelheim Pharmaceuticals
Ridgefield, Connecticut

Rafael Maldonado
University Pompeu Fabra
Barcelona, Spain

John P. Mallamo
Cephalon
West Chester, Pennsylvania

Julie Marasco
Amgen
Thousand Oaks, California

Patrick A. Marcotte
Abbott Laboratories
Abbott Park, Illinois

John Markwell
University of Nebraska
Lincoln, Nebraska

Andrea Marra
Pfizer Global Research and Development
Groton, Connecticut

Shelby A. Martensen
GlaxoSmithKline
Research Triangle Park, North Carolina

David P. Martin
Chadds Ford, Pennsylvania

Graeme R. Martin
Takeda Research Investment
Palo Alto, California

Julio Martin
GlaxoSmithKline
Tres Cantos, Spain

Carlos Martínez-A
Department of Immunology and Oncology
Centro Nacional de Biotecnología/CSIC
Madrid, Spain

Joanne R. Mathiasen
Cephalon
West Chester, Pennsylvania

Kenshi Matsumoto
Lund University Hospital
Lund, Sweden

Daumantas Matulis
University of Minnesota
St. Paul, Minnesota

Joseph R. Maxwell
Amgen
Seattle, Washington

Stuart B. Mazzone
University of Melbourne
Victoria, Australia

Robert A. McArthur
McArthur and Associates
Basel, Switzerland

Dale E. McCall
DuPont Merck Pharmaceuticals
Wilmington, Delaware

Kenneth E. McCarson
University of Kansas Medical Center
Kansas City, Kansas

Laurie K. McCauley
The University of Michigan School of Dentistry
and The University of Michigan Medical School
Ann Arbor, Michigan

Sharon McGonigle
Eisai Research Institute
Andover, Massachusetts

James McKiernan
Columbia University Medical Center
Herbert Irving Comprehensive Cancer Center
New York, New York

Michael McKinney
Mayo Clinic Jacksonville
Jacksonville, Florida

Beth Ann McKenna
Cephalon
West Chester, Pennsylvania

Christopher Mehlin
University of Washington
Seattle, Washington

Ashok K. Mehta
The University of Texas Health Science Center
San Antonio, Texas

Stefania Meini
Menarini Ricerche
Florence, Italy

Mario Mellado
Department of Immunology and Oncology
Centro Nacional de Biotecnología/CSIC
Madrid, Spain

Alison Miller
Discovery Biology
Pfizer Central Research
Sandwich, United Kingdom

Laurence J. Miller
Mayo Clinic
Rochester, Minnesota

Debra M. Mills
Microbiotix
Worcester, Massachusetts

Hongmei Mo
Gilead Sciences
Foster City, California

Ali-Reza Modiri
Biovitrum
Stockholm, Sweden

Hanns Mohler
University of Zurich
Zurich, Switzerland

Eduardo J. Molinari
Abbott Laboratories
Abbott Park, Illinois

David Moncol
GlaxoSmithKline
Research Triangle Park, North Carolina

David Moore
Baylor College of Medicine
Houston, Texas

Jeanne Morgan
Boehringer Ingelheim Pharmaceuticals
Ridgefield, Connecticut

Sonia K. Morgan-Linnell
Baylor College of Medicine
Houston, Texas

Christopher L. Morton
St. Jude Children's Research Hospital
Memphis, Tennessee

Magda F. Morton
Johnson & Johnson Pharmaceutical
La Jolla, California

Jan Mos
Solvay Pharmaceuticals
Weesp, The Netherlands

Paul Moser
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Martha Motherway
Trinity College
Dublin, Ireland

Mary Motyl
Merck
Rahway, New Jersey

Roseanna M. Muccitelli
SmithKline Beecham Pharmaceuticals
King of Prussia, Pennsylvania

Carsten Münk
The Salk Institute for Biological Studies
La Jolla, California

Dennis J. Murphy
GlaxoSmithKline Pharmaceuticals
King of Prussia, Pennsylvania

Donna Mussatto
Abbott Laboratories
Abbott Park, Illinois

S. Jamal Mustafa
West Virginia University
Morgantown, West Virginia

Allen C. Myers
Johns Hopkins University School of Medicine
Baltimore, Maryland

Padma Narayan
The Dow Chemical Company
Midland, Michigan

Norman Nash
Acadia Pharmaceuticals
San Diego, California

Georges Ndikuyeze
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland

Markus F. Neurath
University of Mainz
Mainz, Germany
and University of Erlangen
Erlangen, Germany

Donald Newgreen
Discovery Biology
Pfizer Central Research
Sandwich, United Kingdom

Wende Niforatos
Abbott Laboratories
Abbott Park, Illinois

John L. Nitiss
St. Jude Children's Research Hospital
Memphis, Tennesee

Philip Nunn
Discovery Biology
Pfizer Central Research
Sandwich, United Kingdom

Scott M. O'Grady
Departments of Veterinary and Biomedical Sciences (DRB) and Animal Science (SMO)
University of Minnesota
St. Paul, Minnesota

Berend Olivier
Utrecht Institute for Pharmaceutical Sciences
and Rudolf Magnus Institute of Neuroscience
Utrecht, The Netherlands
and PsychoGenics
Tarrytown, New York
and Yale University School of Medicine
New Haven, Connecticut

Bradley J.S.C. Olson
Michigan State University
East Lansing, Michigan

Emmanuel T. Onua
DeCODE Genetics
Woodridge, Illinois

Timothy J. Opperman
Microbiotix
Worcester, Massachusetts

Mark A. Osinski
Abbott Laboratories
Abbott Park, Illinois

Rachel A. Papa
Children's Cancer Institute Australia for Medical Research
Randwick, New South Wales, Australia

Mariusz Papp
Polish Academy of Sciences
Krakow, Poland

Elsa Paradise
Surface Logix
Brighton, Massachusetts

Serk In Park
The University of Michigan School of Dentistry
Ann Arbor, Michigan

Tari Parmely
The Stowers Institute for Medical Research
Kansas City, Missouri

Régis Parmentier
Development Center
Cephalon France
Maisons Alfort, France

Riccardo Patacchini
Menarini Ricerche
Florence, Italy

Danielle M. Patterson
Baylor College of Medicine
Texas Children's Hospital
Houston, Texas

Daniel Pauletti
Cephalon
West Chester, Pennsylvania

Mark A. Paulik
GlaxoSmithKline
Research Triangle Park, North Carolina

Matthew S. Paulson
Gilead Sciences
Foster City, California

Didier Pélaprat
Hopital St-Antoine
Paris, France

Mary Ann Pelleymounter
Neurocrine Biosciences
San Diego, California

Scott Perschke
NovaScreen Bioscience Corporation
Hanover, Maryland

Sandra Picard
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Roberto Pili
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland
and Roswell Park Cancer Institute
Buffalo, New York

Jenny L. Pokorny
Mayo Clinic
Rochester, Minnesota

Michael P. Pollastri
Northeastern University
Boston, Massachusetts

Roger D. Porsolt
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Christine A. Power
Serono Pharmaceutical Research Institute
Plan-les-Ouates, Switzerland

David R. Poyner
Aston University
Aston Triangle, United Kingdom

Clodagh E. Prendergast
Johnson & Johnson Pharmaceutical
La Jolla, California

Tony Priestley
Schering-Plough Research Institute
Kenilworth, New Jersey

William R. Proctor
Veterans Administration Medical Research Service
Denver, Colorado

Amanda E. I. Proudfoot
Serono Pharmaceutical Research Institute
Plan-les-Ouates, Switzerland

Daniel Provost
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Michael J. Pucci
Achillion Pharmaceuticals
New Haven, Connecticut

M. Teresa Pulido-Rios
Theravance
South San Francisco, California

Anna M. Puzio-Kuter
Columbia University Medical Center
Herbert Irving Comprehensive Cancer Center
New York, New York

Remi Quirion
Douglas Hospital Research Center
Montreal, Canada

Rita Raddatz
Cephalon
West Chester, Pennsylvania

Rajan Radhakrishnan
University of Iowa
Iowa City, Iowa

Vincent Rash
GlaxoSmithKline
Research Triangle Park, North Carolina

Glenn A. Reinhart
Abbott Laboratories
Abbott Park, Illinois

Jonathan P. Renninger
GlaxoSmithKline Pharmaceuticals
King of Prussia, Pennsylvania

Markus Rey
Actelion Pharmaceuticals
Allschwil, Switzerland

Ian J. Reynolds
University of Pittsburgh
Pittsburgh, Pennsylvania

Thomas Rimele
GlaxoSmithKline
Research Triangle Park, North Carolina

Gavin P. Robertson
The College of Medicine and
The Foreman Foundation for Melanoma Research and
The Melanoma Therapeutics Program
Pennsylvania State University
Hershey, Pennsylvania

A. David Rodrigues
Merck Research Laboratories
West Point, Pennsylvania

José Miguel Rodríguez-Frade
Department of Immunology and Oncology
Centro Nacional de Biotecnología/CSIC
Madrid, Spain

Melissa Rogers
University of South Florida
Tampa, Florida

Michael Roguska
Abbott Bioresearch Center
Worcester, Massachusetts

Michael Rosenblatt
Tufts University School of Medicine
Boston, Massachusetts

René Rouet
Université de Caen
Boulogne-Billancourt, France

Sylvain Roux
Porsolt & Partners Pharmacology
Boulogne-Billancourt, France

Bruce Ruggeri
Cephalon
West Chester, Pennsylvania

Evelyne Sablé
Porsolt & Partners Pharmacology
Le Genest-Saint-Isle, France

Sanja Šale
Harvard Medical School
Boston, Massachusetts

Jochen Salfeld
Abbott Bioresearch Center
Worcester, Massachusetts

Brenda C. Salumbides
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Baltimore, Maryland

Jann N. Sarkaria
Mayo Clinic
Rochester, Minnesota

Joachim Sasse
Shriners Hospital
Tampa, Florida

Takuya Sato
Food Science Research Center
House Wellness Foods Corporation
Hyogo, Japan

Howard Sauls
GlaxoSmithKline
Research Triangle Park, North Carolina

Keisuke Sawada
Graduate School of Agricultural Science
Kobe University
Kobe, Japan

Ellen Scepansky
Tufts Medical Center
Boston, Massachusetts

Alexander Scheer
Serono Pharmaceutical Research Institute
Plan-les-Ouates, Switzerland

R. Scherschlicht
Science Writing
Inzlingen, Germany

Rick G. Schnellmann
Medical University of South Carolina
Charleston, South Carolina

Mark A. Schroeder
Mayo Clinic
Rochester, Minnesota

Brian Schultz
Gilead Sciences
Foster City, California

Victoria E.S. Scott
Abbott Laboratories
Abbott Park, Illinois

Catherine Seager
Columbia University Medical Center
Herbert Irving Comprehensive Cancer Center
New York, New York

Matthew M. Seavey
Cephalon
West Chester, Pennsylvania

Roland Seifert
Universität Regensburg
Regensburg, Germany

Terese R. Seifert
Abbott Laboratories
Abbott Park, Illinois

Ze'ev Seltzer
University of Toronto
Toronto, Canada

Elliot L. Servais
Memorial Sloan-Kettering Cancer Center
New York, New York

Patrick M. Sexton
Monash University
Victoria, Australia

Nigel P. Shankley
Johnson & Johnson Pharmaceutical
La Jolla, California

Arati Sharma
Pennsylvania State University College of Medicine
Hershey, Pennsylvania

Thomas K. Shaughnessy
Abbott Laboratories
Abbott Park, Illinois

Jen Sheen
Massachusetts General Hospital and Harvard Medical School
Boston, Massachusetts

Char-Chang Shieh
Abbott Laboratories
Abbott Park, Illinois

Victor Shifrin
International Consulting, Inc.
Auburndale, Massachusetts

Jason M. Shohet
Baylor College of Medicine
Texas Children's Hospital
Houston, Texas

Pam A. Silver
Dana-Farber Cancer Institute
Boston, Massachusetts

Peter S. Silverstein
University of Kansas
Lawrence, Kansas

Alain Simonnard
Centre International de Toxicologie (CIT)
Evreux, France

David Skyba
University of Iowa
Iowa City, Iowa

Kathleen A. Sluka
University of Iowa
Iowa City, Iowa

Barbara S. Slusher
Guilford Pharmaceuticals
Baltimore, Maryland

Trevor G. Smart
University College London
London, United Kingdom

Carole L. Smith
Amgen
Seattle, Washington

Ronald D. Smith
Merck
Whitehouse Station, New Jersey

Dulce Soler
Millennium Pharmaceuticals
Cambridge, Massachusetts

Yves Somers
Johnson & Johnson
Beerse, Belgium

Roel L.H.M.G. Spätjens
Cardiovascular Research Institute Maastricht
Maastricht University Medical Centre
Maastricht, The Netherlands

Roger D. Spealman
New England Regional Primate Research Center
Harvard Medical School
Southborough, Massachusetts

Michael Stashko
Abbott Laboratories
Abbott Park, Illinois

Tod Steinfeld
Theravance
South San Francisco, California

Troy Stevens
University of South Alabama College of Medicine
Mobile, Alabama

Marina Strakhova
Abbott Laboratories
Abbott Park, Illinois

Brian Strassle
Wyeth Research
Princeton, New Jersey

Jay C. Strum
GlaxoSmithKline
Research Triangle Park, North Carolina

Joan S. Stuart
GlaxoSmithKline
Research Triangle Park, North Carolina

Kristine L. Stump
Cephalon
West Chester, Pennsylvania

James P. Sullivan
Abbott Laboratories
Abbott Park, Illinois

Jan Svartengren
Biovitrum
Stockholm, Sweden

David A. Sykes
Novartis Institutes for Biomedical Research
Horsham, West Sussex, United Kingdom

David A. Taylor
The Brody School of Medicine at East Carolina University
Greenville, North Carolina

Ard Teisman
Johnson & Johnson
Beerse, Belgium

Elena Ter-Ovanesyan
Surface Logix
Brighton, Massachusetts

Philip Thomas
University College London
London, United Kingdom

W. Joseph Thompson
Cell Pathways
Horsham, Pennsylvania

Maharaj K. Ticku
The University of Texas Health Science Center
San Antonio, Texas

Carol W. Tiffany
Guilford Pharmaceuticals
Baltimore, Maryland

Pieter B.M.W.M. Timmermans
Tularik
South San Francisco, California

Keith F. Tipton
Trinity College
Dublin, Ireland

James Trevillyan
Abbott Laboratories
Abbott Park, Illinois

David J. Triggle
The State University of New York
Buffalo, New York

David G. Trist
Glaxo Wellcome
Verona, Italy

Manabu Ueda
Graduate School of Agricultural Science
Kobe University
Kobe, Japan

Jean-Pierre Valentin
Safety Assessment UK
AstraZeneca R&D
Cheshire, United Kingdom

Tim van Biesen
Abbott Laboratories
Abbott Park, Illinois

Olga Valverde
University Pompeu Fabra
Barcelona, Spain

Jan A.M. van der Heyden
Solvay Pharmaceuticals
Weesp, The Netherlands

Henk J. van der Linde
Johnson & Johnson
Beerse, Belgium

Bruno Van Deuren
Johnson & Johnson
Beerse, Belgium

Richard A. Van Etten
Tufts Medical Center
Boston, Massachusetts

Ruud van Oorschot
Utrecht Institute for Pharmaceutical Sciences
and Rudolf Magnus Institute of Neuroscience
Utrecht, The Netherlands

P. Monika Verdouw
Utrecht Institute for Pharmaceutical Sciences
and Rudolf Magnus Institute of Neuroscience
Utrecht, The Netherlands

Joanne L. Viney
Amgen
Thousand Oaks, California

Christiaan Vinkers
Utrecht Institute for Pharmaceutical Sciences
and Rudolf Magnus Institute of Neuroscience
Utrecht, The Netherlands

Naomi P. Visanji
Toronto Western Research Institute
Toronto, Ontario, Canada

Paul G.A. Volders
Cardiovascular Research Institute Maastricht
Maastricht University Medical Centre
Maastricht, The Netherlands

Phyllis Wachsberger
Thomas Jefferson University
Philadelphia, Pennsylvania

Stéphanie Wagner
Neurofit SAS
Illkirch, France

Maximilian J. Waldner
University of Mainz
Mainz, Germany
and University of Erlangen
Erlangen, Germany

Dianne M. Walters
Laboratory of Respiratory Biology
National Institute of Environmental Health Sciences
National Institutes of Health
Research Triangle Park, North Carolina

Ruth Wang
Gilead Sciences
Foster City, California

Jeffrey F. Waring
Abbott Laboratories
Abbott Park, Illinois

Simon Watkins
University of Pittsburgh Medical School
Pittsburgh, Pennsylvania

Christian A. Watson
GlaxoSmithKline Molecular Discovery Research
Research Triangle Park, North Carolina

Nikki Watson
Theravance
South San Francisco, California

Gillian F. Watt
James Black Foundation
London, United Kingdom

Steven J. Weber
Pfizer Global Research & Development
Ann Arbor, Michigan

Craig D. Wegner
Abbott Laboratories
Abbott Park, Illinois

C. Wells
Scottish Biomedical
Glasgow, Scotland, United Kingdom

Roseanne S. Wexler
Surface Logix
Brighton, Massachusetts

Kristi L. Whiteaker
Abbott Laboratories
Abbott Park, Illinois

Phyllis E. Whiteley
Roche Bioscience
Palo Alto, California

Alan D. Wickenden
Icagen
Durham, North Carolina

Michael Williams
Cephalon
West Chester, Pennsylvania

Ian Williamson
Discovery Biology
Pfizer Central Research
Sandwich, United Kingdom

Rolf T. Windh
Adolor
Exton, Pennsylvania

Pancras C. Wong
DuPont Merck Pharmaceuticals
Wilmington, Delaware

David F. Woodward
Allergan
Irvine, California

Jerry L. Workman
The Stowers Institute for Medical Research
Kansas City, Missouri

Joseph R. Woska, Jr.
Boehringer Ingelheim Pharmaceuticals
Ridgefield, Connecticut

Kenneth K. Wu
Merck Research Laboratories
Rahway, New Jersey

Norio Yamamoto
Food Science Research Center
House Wellness Foods Corporation
Hyogo, Japan

Guangwei Yang
Achillion Pharmaceuticals
New Haven, Connecticut

Huiling Yang
Gilead Sciences
Foster City, California

Tingting Yao
The Stowers Institute for Medical Research
Kansas City, Missouri

Katherine Young
Merck Research Laboratories
Rahway, New Jersey

Lynn Zechiedrich
Baylor College of Medicine
Houston, Texas

Rolf Zeller
University of Utrecht
The Netherlands

Theo J.J. Zethof
Solvay Pharmaceuticals
Weesp, The Netherlands

Fang L. Zhang
Schering-Plough Research Institute
Kenilworth, New Jersey

Jie Zhang
Guilford Pharmaceuticals
Baltimore, Maryland

Yongsen Zhao
Achillion Pharmaceuticals
New Haven, Connecticut

Wei Zheng
Merck
North Wales, Pennsylvania

Anruo Zou
Icagen
Durham, North Carolina